There are 751.92 miles from Saint Louis to Jacksonville in southeast direction and 898.95 miles by car, following the route.
Saint Louis and Jacksonville are 12 hours 50 mins far apart, if you drive non-stop.
This is the fastest route from Saint Louis, MO to Jacksonville, FL. The halfway point is .
Please note the time difference between Saint Louis, MO and Jacksonville, FL is 1 hour. The current time in Saint Louis is 1:53 pm and the current time in Jacksonville is 2:53 pm.
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