There are 240.42 miles from Saint Louis to Memphis in south direction and 283.25 miles (455.85 kilometers) by car, following the I-55 route.
Saint Louis and Memphis are 3 hours 57 mins far apart, if you drive non-stop.
This is the fastest route from Saint Louis, MO to Memphis, TN. The halfway point is .
Saint Louis, MO and Memphis, TN are in the same time zone (CDT). Current time in both locations is 5:37 am.
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