There are 38.61 miles from San Francisco to Santa Clara in southeast direction and 44 miles (70.81 kilometers) by car, following the US-101 S route.
San Francisco and Santa Clara are 46 minutes far apart, if you drive non-stop .
This is the fastest route from San Francisco, CA to Santa Clara, CA. The halfway point is San Carlos, CA.
San Francisco, CA and Santa Clara, CA are in the same time zone (PDT). Current time in both locations is 3:23 pm.
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