There are 66.53 miles from South Portland to Appleton in northeast direction and 85 miles (136.79 kilometers) by car, following the I-295 N and US-1 route.
South Portland and Appleton are 1 hour 47 mins far apart, if you drive non-stop .
This is the fastest route from South Portland, ME to Appleton, ME. The halfway point is Richmond, ME.
South Portland, ME and Appleton, ME are in the same time zone (EDT). Current time in both locations is 10:18 am.
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