There are 535.68 miles from Venice to Greenville in north direction and 662 miles (1,065.39 kilometers) by car, following the FL 681 route.
Venice and Greenville are 12 hours 7 mins far apart, if you drive non-stop.
This is the fastest route from Venice, FL to Greenville, SC. The halfway point is Tifton, GA.
Venice, FL and Greenville, SC are in the same time zone (Eastern Daylight Time). Current time in both locations is 1:58 am.
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