Distance between cities › USA › Ohio › Andover, OH › Distance from Andover to Middlesex Book Hotels

Distance from Andover, OH to Middlesex, NC

Distance

561 mi

Time

11 hours 9 mins

Gas Cost

$52 - $102

There are 421.64 miles from Andover to Middlesex in southeast direction and 561 miles (902.84 kilometers) by car, following the I-95 route.

Andover and Middlesex are 11 hours 9 mins far apart, if you drive non-stop .

This is the fastest route from Andover, OH to Middlesex, NC.

Andover, OH and Middlesex, NC are in the same time zone (EDT). Current time in both locations is 2:19 pm.

Any questions or tips to share?

Share with fellow travellers any question or tips about the route from Andover, OH to Middlesex, NC:

Lowest Price Rental Cars in Andover, OH

Planning on renting a car to go from Andover, OH to Middlesex, NC? Here there are some offers to rent a car in Andover, OH

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Andover »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 22.52 gallons of gas to cover the route between Andover, OH and Middlesex, NC.

The estimated cost of gas to go from Andover to Middlesex is $73.45.

During the route, an average car will release 441.14 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Andover, OH and Middlesex, NC

If you want to meet halfway between Andover, OH and Middlesex, NC or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.029087 and -78.26871, or 39º 1' 44.7132" N, 78º 16' 7.356" W. This location is 280.33 miles away from Andover, OH and Middlesex, NC and it would take approximately 5 hours 34 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Middletown, VA, situated 275 miles from Andover, OH and 288 miles from Middlesex, NC. It would take 5 hours 42 mins to go from Andover to Middletown and 5 hours 32 mins to go from Middlesex to Middletown.