There are 335.84 miles from Appalachia to Issue in northeast direction and 408 miles (656.61 kilometers) by car, following the I-81 and US-11 route.
Appalachia and Issue are 8 hours 37 mins far apart, if you drive non-stop .
This is the fastest route from Appalachia, VA to Issue, MD.
Appalachia, VA and Issue, MD are in the same time zone (EDT). Current time in both locations is 12:20 pm.
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