There are 5.53 miles from Cairo to Jacksonville in northwest direction and 6 miles (9.66 kilometers) by car, following the US-63 route.
Cairo and Jacksonville are 8 minutes far apart, if you drive non-stop .
This is the fastest route from Cairo, MO to Jacksonville, MO.
Cairo, MO and Jacksonville, MO are in the same time zone (CDT). Current time in both locations is 4:57 pm.
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