Distance between cities › USA › Missouri › Cameron, MO › Distance from Cameron to Lancaster Book Hotels

Distance from Cameron, MO to Lancaster, KY

Distance

626 mi

Time

12 hours 4 mins

Gas Cost

$58 - $114

There are 541.10 miles from Cameron to Lancaster in southeast direction and 626 miles (1,007.45 kilometers) by car, following the I-64 route.

Cameron and Lancaster are 12 hours 4 mins far apart, if you drive non-stop .

This is the fastest route from Cameron, MO to Lancaster, KY.

Please note the time difference between Cameron, MO and Lancaster, KY is 1 hour. The current time in Cameron is 10:35 pm and the current time in Lancaster is 11:35 pm.

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Lowest Price Rental Cars in Cameron, MO

Planning on renting a car to go from Cameron, MO to Lancaster, KY? Here there are some offers to rent a car in Cameron, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Cameron »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 25.16 gallons of gas to cover the route between Cameron, MO and Lancaster, KY.

The estimated cost of gas to go from Cameron to Lancaster is $82.07.

During the route, an average car will release 492.90 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Cameron, MO and Lancaster, KY

If you want to meet halfway between Cameron, MO and Lancaster, KY or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 38.440314 and -89.531591, or 38º 26' 25.1304" N, 89º 31' 53.7276" W. This location is 313.22 miles away from Cameron, MO and Lancaster, KY and it would take approximately 6 hours 2 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Okawville, IL, situated 315 miles from Cameron, MO and 314 miles from Lancaster, KY. It would take 6 hours 14 mins to go from Cameron to Okawville and 5 hours 55 mins to go from Lancaster to Okawville.