Distance between cities › USA › Missouri › Cascade, MO › Distance from Cascade to Cairo Book Hotels

Distance from Cascade, MO to Cairo, NE

Distance

648 mi

Time

12 hours 31 mins

Gas Cost

$60 - $117

There are 514.46 miles from Cascade to Cairo in northwest direction and 648 miles (1,042.85 kilometers) by car, following the I-70 and US-40 route.

Cascade and Cairo are 12 hours 31 mins far apart, if you drive non-stop .

This is the fastest route from Cascade, MO to Cairo, NE.

Cascade, MO and Cairo, NE are in the same time zone (CDT). Current time in both locations is 2:45 am.

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Lowest Price Rental Cars in Cascade, MO

Planning on renting a car to go from Cascade, MO to Cairo, NE? Here there are some offers to rent a car in Cascade, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Cascade »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 26.02 gallons of gas to cover the route between Cascade, MO and Cairo, NE.

The estimated cost of gas to go from Cascade to Cairo is $84.88.

During the route, an average car will release 509.82 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Cascade, MO and Cairo, NE

If you want to meet halfway between Cascade, MO and Cairo, NE or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.033205 and -94.295978, or 39º 1' 59.538" N, 94º 17' 45.5208" W. This location is 323.97 miles away from Cascade, MO and Cairo, NE and it would take approximately 6 hours 15 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Lake Tapawingo, MO, situated 327 miles from Cascade, MO and 324 miles from Cairo, NE. It would take 6 hours 34 mins to go from Cascade to Lake Tapawingo and 6 hours 4 mins to go from Cairo to Lake Tapawingo.

Major City Closest to Halfway Point

The major city closest to the halfway point between Cascade, MO and Cairo, NE is Kansas City, MO, situated 342 miles from Cascade, MO and 302 miles from Cairo, NE. It would take 6 hours 51 mins to go from Cascade to Kansas City and 5 hours 41 mins to go from Cairo to Kansas City.