Distance between cities › USA › Missouri › Cascade, MO › Distance from Cascade to Clemson Book Hotels

Distance from Cascade, MO to Clemson, SC

Distance

623 mi

Time

12 hours 19 mins

Gas Cost

$58 - $113

There are 452.91 miles from Cascade to Clemson in southeast direction and 623 miles (1,002.62 kilometers) by car, following the I-24 route.

Cascade and Clemson are 12 hours 19 mins far apart, if you drive non-stop .

This is the fastest route from Cascade, MO to Clemson, SC.

Please note the time difference between Cascade, MO and Clemson, SC is 1 hour. The current time in Cascade is 10:02 am and the current time in Clemson is 11:02 am.

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Lowest Price Rental Cars in Cascade, MO

Planning on renting a car to go from Cascade, MO to Clemson, SC? Here there are some offers to rent a car in Cascade, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Cascade »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 25.02 gallons of gas to cover the route between Cascade, MO and Clemson, SC.

The estimated cost of gas to go from Cascade to Clemson is $81.63.

During the route, an average car will release 490.26 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Cascade, MO and Clemson, SC

If you want to meet halfway between Cascade, MO and Clemson, SC or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.717275 and -86.317198, or 35º 43' 2.19" N, 86º 19' 1.9128" W. This location is 311.54 miles away from Cascade, MO and Clemson, SC and it would take approximately 6 hours 9 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Christiana, TN, situated 307 miles from Cascade, MO and 323 miles from Clemson, SC. It would take 6 hours 24 mins to go from Cascade to Christiana and 6 hours 13 mins to go from Clemson to Christiana.

Major City Closest to Halfway Point

The major city closest to the halfway point between Cascade, MO and Clemson, SC is Murfreesboro, TN, situated 298 miles from Cascade, MO and 327 miles from Clemson, SC. It would take 6 hours 15 mins to go from Cascade to Murfreesboro and 6 hours 11 mins to go from Clemson to Murfreesboro.