Distance between cities › USA › Missouri › Cascade, MO › Distance from Cascade to Florence Book Hotels

Distance from Cascade, MO to Florence, MS

Distance

409 mi

Time

8 hours 9 mins

Gas Cost

$38 - $74

There are 355.64 miles from Cascade to Florence in south direction and 409 miles (658.22 kilometers) by car, following the I-55 route.

Cascade and Florence are 8 hours 9 mins far apart, if you drive non-stop .

This is the fastest route from Cascade, MO to Florence, MS.

Cascade, MO and Florence, MS are in the same time zone (CDT). Current time in both locations is 5:29 am.

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Lowest Price Rental Cars in Cascade, MO

Planning on renting a car to go from Cascade, MO to Florence, MS? Here there are some offers to rent a car in Cascade, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Cascade »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 16.41 gallons of gas to cover the route between Cascade, MO and Florence, MS.

The estimated cost of gas to go from Cascade to Florence is $53.53.

During the route, an average car will release 321.51 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Cascade, MO and Florence, MS

If you want to meet halfway between Cascade, MO and Florence, MS or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.034326 and -90.002616, or 35º 2' 3.5736" N, 90º 0' 9.4176" W. This location is 204.31 miles away from Cascade, MO and Florence, MS and it would take approximately 4 hours 4 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest city to the halfway point is Southaven, MS, situated 202 miles from Cascade, MO and 207 miles from Florence, MS. It would take 4 hours 23 mins to go from Cascade to Southaven and 3 hours 48 mins to go from Florence to Southaven.

Major City Closest to Halfway Point

The major city closest to the halfway point between Cascade, MO and Florence, MS is Memphis, TN, situated 191 miles from Cascade, MO and 219 miles from Florence, MS. It would take 4 hours 8 mins to go from Cascade to Memphis and 4 hours 5 mins to go from Florence to Memphis.