Distance between cities › USA › Missouri › Cascade, MO › Distance from Cascade to Lexington Book Hotels

Distance from Cascade, MO to Lexington, MS

Distance

346 mi

Time

7 hours 1 min

Gas Cost

$32 - $63

There are 289.50 miles from Cascade to Lexington in south direction and 346 miles (556.83 kilometers) by car, following the I-55 route.

Cascade and Lexington are 7 hours 1 min far apart, if you drive non-stop .

This is the fastest route from Cascade, MO to Lexington, MS.

Cascade, MO and Lexington, MS are in the same time zone (CDT). Current time in both locations is 6:23 am.

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Lowest Price Rental Cars in Cascade, MO

Planning on renting a car to go from Cascade, MO to Lexington, MS? Here there are some offers to rent a car in Cascade, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Cascade »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 13.90 gallons of gas to cover the route between Cascade, MO and Lexington, MS.

The estimated cost of gas to go from Cascade to Lexington is $45.34.

During the route, an average car will release 272.34 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Cascade, MO and Lexington, MS

If you want to meet halfway between Cascade, MO and Lexington, MS or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.336522 and -90.267314, or 35º 20' 11.4792" N, 90º 16' 2.3304" W. This location is 173.06 miles away from Cascade, MO and Lexington, MS and it would take approximately 3 hours 30 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Clarkedale, AR, situated 173 miles from Cascade, MO and 175 miles from Lexington, MS. It would take 3 hours 49 mins to go from Cascade to Clarkedale and 3 hours 16 mins to go from Lexington to Clarkedale.

Major City Closest to Halfway Point

The major city closest to the halfway point between Cascade, MO and Lexington, MS is Memphis, TN, situated 191 miles from Cascade, MO and 157 miles from Lexington, MS. It would take 4 hours 8 mins to go from Cascade to Memphis and 2 hours 56 mins to go from Lexington to Memphis.