Distance between cities › USA › Missouri › Cascade, MO › Distance from Cascade to Madison Book Hotels

Distance from Cascade, MO to Madison, MS

Distance

386 mi

Time

7 hours 41 mins

Gas Cost

$36 - $70

There are 334.37 miles from Cascade to Madison in south direction and 386 miles (621.21 kilometers) by car, following the I-55 route.

Cascade and Madison are 7 hours 41 mins far apart, if you drive non-stop .

This is the fastest route from Cascade, MO to Madison, MS.

Cascade, MO and Madison, MS are in the same time zone (CDT). Current time in both locations is 7:01 am.

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Lowest Price Rental Cars in Cascade, MO

Planning on renting a car to go from Cascade, MO to Madison, MS? Here there are some offers to rent a car in Cascade, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Cascade »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 15.50 gallons of gas to cover the route between Cascade, MO and Madison, MS.

The estimated cost of gas to go from Cascade to Madison is $50.55.

During the route, an average car will release 303.62 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Cascade, MO and Madison, MS

If you want to meet halfway between Cascade, MO and Madison, MS or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.137025 and -90.0926, or 35º 8' 13.29" N, 90º 5' 33.36" W. This location is 192.94 miles away from Cascade, MO and Madison, MS and it would take approximately 3 hours 50 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest and also the major city is Memphis, TN, situated 190.7 miles from Cascade, MO and 196.62 miles from Madison, MS. It would take 4 hours 8 mins to go from Cascade to Memphis and 3 hours 36 mins to go from Madison to Memphis.