Distance between cities › USA › Missouri › Cascade, MO › Distance from Cascade to Middletown Book Hotels

Distance from Cascade, MO to Middletown, VA

Distance

822 mi

Time

16 hours

Gas Cost

$77 - $149

There are 661.62 miles from Cascade to Middletown in east direction and 822 miles (1,322.88 kilometers) by car, following the I-64 route.

Cascade and Middletown are 16 hours far apart, if you drive non-stop .

This is the fastest route from Cascade, MO to Middletown, VA.

Please note the time difference between Cascade, MO and Middletown, VA is 1 hour. The current time in Cascade is 5:38 am and the current time in Middletown is 6:38 am.

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Lowest Price Rental Cars in Cascade, MO

Planning on renting a car to go from Cascade, MO to Middletown, VA? Here there are some offers to rent a car in Cascade, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Cascade »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 33.03 gallons of gas to cover the route between Cascade, MO and Middletown, VA.

The estimated cost of gas to go from Cascade to Middletown is $107.73.

During the route, an average car will release 647.04 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Cascade, MO and Middletown, VA

If you want to meet halfway between Cascade, MO and Middletown, VA or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 38.030734 and -84.086758, or 38º 1' 50.6424" N, 84º 5' 12.3288" W. This location is 411.17 miles away from Cascade, MO and Middletown, VA and it would take approximately 8 hours to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Winchester, KY, situated 407 miles from Cascade, MO and 417 miles from Middletown, VA. It would take 8 hours 17 mins to go from Cascade to Winchester and 7 hours 48 mins to go from Middletown to Winchester.

Major City Closest to Halfway Point

The major city closest to the halfway point between Cascade, MO and Middletown, VA is Lexington, KY, situated 386 miles from Cascade, MO and 436 miles from Middletown, VA. It would take 7 hours 51 mins to go from Cascade to Lexington and 8 hours 13 mins to go from Middletown to Lexington.