Distance between cities › USA › Missouri › Cascade, MO › Distance from Cascade to Wayne Book Hotels

Distance from Cascade, MO to Wayne, WV

Distance

525 mi

Time

10 hours 29 mins

Gas Cost

$49 - $95

There are 432.12 miles from Cascade to Wayne in east direction and 525 miles (844.91 kilometers) by car, following the I-64 route.

Cascade and Wayne are 10 hours 29 mins far apart, if you drive non-stop .

This is the fastest route from Cascade, MO to Wayne, WV.

Please note the time difference between Cascade, MO and Wayne, WV is 1 hour. The current time in Cascade is 9:37 am and the current time in Wayne is 10:37 am.

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Lowest Price Rental Cars in Cascade, MO

Planning on renting a car to go from Cascade, MO to Wayne, WV? Here there are some offers to rent a car in Cascade, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Cascade »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 21.10 gallons of gas to cover the route between Cascade, MO and Wayne, WV.

The estimated cost of gas to go from Cascade to Wayne is $68.81.

During the route, an average car will release 413.30 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Cascade, MO and Wayne, WV

If you want to meet halfway between Cascade, MO and Wayne, WV or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 37.416715 and -86.406718, or 37º 25' 0.174" N, 86º 24' 24.1848" W. This location is 262.64 miles away from Cascade, MO and Wayne, WV and it would take approximately 5 hours 14 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Millwood, KY, situated 267 miles from Cascade, MO and 260 miles from Wayne, WV. It would take 5 hours 40 mins to go from Cascade to Millwood and 4 hours 57 mins to go from Wayne to Millwood.