Distance between cities › USA › Missouri › Guilford, MO › Distance from Guilford to Issue Book Hotels

Distance from Guilford, MO to Issue, MD

Distance

1,161 mi

Time

22 hours 40 mins

Gas Cost

$108 - $210

There are 961.67 miles from Guilford to Issue in east direction and 1,161 miles (1,868.45 kilometers) by car, following the US-36 route.

Guilford and Issue are 22 hours 40 mins far apart, if you drive non-stop .

This is the fastest route from Guilford, MO to Issue, MD.

Please note the time difference between Guilford, MO and Issue, MD is 1 hour. The current time in Guilford is 9:56 pm and the current time in Issue is 10:56 pm.

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Lowest Price Rental Cars in Guilford, MO

Planning on renting a car to go from Guilford, MO to Issue, MD? Here there are some offers to rent a car in Guilford, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Guilford »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 46.62 gallons of gas to cover the route between Guilford, MO and Issue, MD.

The estimated cost of gas to go from Guilford to Issue is $152.07.

During the route, an average car will release 913.33 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Guilford, MO and Issue, MD

If you want to meet halfway between Guilford, MO and Issue, MD or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.853328 and -85.417018, or 39º 51' 11.9808" N, 85º 25' 1.2648" W. This location is 580.39 miles away from Guilford, MO and Issue, MD and it would take approximately 11 hours 20 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Spiceland, IN, situated 574 miles from Guilford, MO and 590 miles from Issue, MD. It would take 11 hours 3 mins to go from Guilford to Spiceland and 11 hours 44 mins to go from Issue to Spiceland.