There are 589.41 miles from Harrisburg to Appleton in southeast direction and 727 miles (1,169.99 kilometers) by car, following the I-29 route.
Harrisburg and Appleton are 13 hours 15 mins far apart, if you drive non-stop .
This is the fastest route from Harrisburg, SD to Appleton, AR.
Harrisburg, SD and Appleton, AR are in the same time zone (CDT). Current time in both locations is 8:36 pm.
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