There are 126.59 miles from Harrisburg to Appleton in northeast direction and 161 miles (259.10 kilometers) by car, following the I-29 route.
Harrisburg and Appleton are 3 hours 19 mins far apart, if you drive non-stop .
This is the fastest route from Harrisburg, SD to Appleton, MN. The halfway point is Toronto, SD.
Harrisburg, SD and Appleton, MN are in the same time zone (CDT). Current time in both locations is 8:35 pm.
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