Distance between cities › USA › Mississippi › Isola, MS › Distance from Isola to Appleton Book Hotels

Distance from Isola, MS to Appleton, NY

Distance

1,096 mi

Time

21 hours 13 mins

Gas Cost

$100 - $195

There are 948.41 miles from Isola to Appleton in northeast direction and 1,096 miles (1,763.84 kilometers) by car, following the I-40 route.

Isola and Appleton are 21 hours 13 mins far apart, if you drive non-stop .

This is the fastest route from Isola, MS to Appleton, NY. The halfway point is Sulphur, KY.

Please note the time difference between Isola, MS and Appleton, NY is 1 hour. The current time in Isola is 5:19 pm and the current time in Appleton is 6:19 pm.

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Lowest Price Rental Cars in Isola, MS

Planning on renting a car to go from Isola, MS to Appleton, NY? Here there are some offers to rent a car in Isola, MS

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Isola »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 44.02 gallons of gas to cover the route between Isola, MS and Appleton, NY.

The estimated cost of gas to go from Isola to Appleton is $141.03.

During the route, an average car will release 862.38 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Isola, MS and Appleton, NY

If you want to meet halfway between Isola, MS and Appleton, NY or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 38.482895 and -85.273117, or 38º 28' 58.422" N, 85º 16' 23.2212" W. This location is 548.01 miles away from Isola, MS and Appleton, NY and it would take approximately 10 hours 36 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Sulphur, KY, situated 570 miles from Isola, MS and 537 miles from Appleton, NY. It would take 9 hours 20 mins to go from Isola to Sulphur and 8 hours 53 mins to go from Appleton to Sulphur.

Major City Closest to Halfway Point

The major city closest to the halfway point between Isola, MS and Appleton, NY is Louisville, KY, situated 535 miles from Isola, MS and 569 miles from Appleton, NY. It would take 8 hours 44 mins to go from Isola to and 9 hours 22 mins to go from Appleton to Louisville.