Distance between cities › USA › Mississippi › Isola, MS › Distance from Isola to Upton Book Hotels

Distance from Isola, MS to Upton, MA

Distance

1,405 mi

Time

1 day 3 hours

Gas Cost

$129 - $250

There are 1,202.76 miles from Isola to Upton in northeast direction and 1,405 miles (2,261.13 kilometers) by car, following the I-81 route.

Isola and Upton are 1 day 3 hours far apart, if you drive non-stop .

This is the fastest route from Isola, MS to Upton, MA.

Please note the time difference between Isola, MS and Upton, MA is 1 hour. The current time in Isola is 12:30 am and the current time in Upton is 1:30 am.

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Lowest Price Rental Cars in Isola, MS

Planning on renting a car to go from Isola, MS to Upton, MA? Here there are some offers to rent a car in Isola, MS

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Isola »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 56.42 gallons of gas to cover the route between Isola, MS and Upton, MA.

The estimated cost of gas to go from Isola to Upton is $180.76.

During the route, an average car will release 1,105.33 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Isola, MS and Upton, MA

If you want to meet halfway between Isola, MS and Upton, MA or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 36.976967 and -80.838449, or 36º 58' 37.0812" N, 80º 50' 18.4164" W. This location is 702.39 miles away from Isola, MS and Upton, MA and it would take approximately 13 hours 38 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Barren Springs, VA, situated 722 miles from Isola, MS and 696 miles from Upton, MA. It would take 13 hours 45 mins to go from Isola to Barren Springs and 13 hours 55 mins to go from Upton to Barren Springs.