Distance between cities › USA › Texas › La Mesa, TX › Distance from La Mesa to Guymon Book Hotels

Distance from La Mesa, TX to Guymon, OK

Distance

305 mi

Time

5 hours 22 mins

Gas Cost

$28 - $54

There are 273.88 miles from La Mesa to Guymon in north direction and 305 miles (490.85 kilometers) by car, following the I-27 and US-87 route.

La Mesa and Guymon are 5 hours 22 mins far apart, if you drive non-stop .

This is the fastest route from La Mesa, TX to Guymon, OK. The halfway point is Canyon, TX.

La Mesa, TX and Guymon, OK are in the same time zone (CDT). Current time in both locations is 5:19 pm.

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Lowest Price Rental Cars in La Mesa, TX

Planning on renting a car to go from La Mesa, TX to Guymon, OK? Here there are some offers to rent a car in La Mesa, TX

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in La Mesa »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 12.24 gallons of gas to cover the route between La Mesa, TX and Guymon, OK.

The estimated cost of gas to go from La Mesa to Guymon is $39.21.

During the route, an average car will release 239.78 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between La Mesa, TX and Guymon, OK

If you want to meet halfway between La Mesa, TX and Guymon, OK or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 34.870701 and -101.848236, or 34º 52' 14.5236" N, 101º 50' 53.6496" W. This location is 152.37 miles away from La Mesa, TX and Guymon, OK and it would take approximately 2 hours 41 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Canyon, TX, situated 165 miles from La Mesa, TX and 140 miles from Guymon, OK. It would take 3 hours 2 mins to go from La Mesa to Canyon and 2 hours 38 mins to go from Guymon to Canyon.

Major City Closest to Halfway Point

The major city closest to the halfway point between La Mesa, TX and Guymon, OK is Amarillo, TX, situated 184 miles from La Mesa, TX and 121 miles from Guymon, OK. It would take 3 hours 18 mins to go from La Mesa to and 2 hours 20 mins to go from Guymon to Amarillo.