Distance between cities › USA › Texas › La Mesa, TX › Distance from La Mesa to Sioux Falls Book Hotels

Distance from La Mesa, TX to Sioux Falls, SD

Distance

966 mi

Time

18 hours 2 mins

Gas Cost

$90 - $175

There are 798.31 miles from La Mesa to Sioux Falls in northeast direction and 966 miles (1,554.63 kilometers) by car, following the I-135 and US-81 route.

La Mesa and Sioux Falls are 18 hours 2 mins far apart, if you drive non-stop .

This is the fastest route from La Mesa, TX to Sioux Falls, SD.

La Mesa, TX and Sioux Falls, SD are in the same time zone (CDT). Current time in both locations is 7:25 am.

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Lowest Price Rental Cars in La Mesa, TX

Planning on renting a car to go from La Mesa, TX to Sioux Falls, SD? Here there are some offers to rent a car in La Mesa, TX

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in La Mesa »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 38.79 gallons of gas to cover the route between La Mesa, TX and Sioux Falls, SD.

The estimated cost of gas to go from La Mesa to Sioux Falls is $126.55.

During the route, an average car will release 760.05 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between La Mesa, TX and Sioux Falls, SD

If you want to meet halfway between La Mesa, TX and Sioux Falls, SD or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 38.127399 and -99.168551, or 38º 7' 38.6364" N, 99º 10' 6.7836" W. This location is 482.98 miles away from La Mesa, TX and Sioux Falls, SD and it would take approximately 9 hours 1 min to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Larned, KS, situated 489 miles from La Mesa, TX and 477 miles from Sioux Falls, SD. It would take 8 hours 57 mins to go from La Mesa to Larned and 9 hours 5 mins to go from Sioux Falls to Larned.