Distance between cities › USA › South Carolina › Leesville, SC › Distance from Leesville to Cairo Book Hotels

Distance from Leesville, SC to Cairo, OH

Distance

616 mi

Time

12 hours 13 mins

Gas Cost

$57 - $112

There are 498.20 miles from Leesville to Cairo in northwest direction and 616 miles (991.36 kilometers) by car, following the I-26 route.

Leesville and Cairo are 12 hours 13 mins far apart, if you drive non-stop .

This is the fastest route from Leesville, SC to Cairo, OH.

Leesville, SC and Cairo, OH are in the same time zone (EDT). Current time in both locations is 11:13 am.

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Lowest Price Rental Cars in Leesville, SC

Planning on renting a car to go from Leesville, SC to Cairo, OH? Here there are some offers to rent a car in Leesville, SC

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Leesville »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 24.73 gallons of gas to cover the route between Leesville, SC and Cairo, OH.

The estimated cost of gas to go from Leesville to Cairo is $80.65.

During the route, an average car will release 484.42 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Leesville, SC and Cairo, OH

If you want to meet halfway between Leesville, SC and Cairo, OH or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 36.871906 and -83.880357, or 36º 52' 18.8616" N, 83º 52' 49.2852" W. This location is 307.83 miles away from Leesville, SC and Cairo, OH and it would take approximately 6 hours 6 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Barbourville, KY, situated 303 miles from Leesville, SC and 314 miles from Cairo, OH. It would take 6 hours 17 mins to go from Leesville to Barbourville and 5 hours 58 mins to go from Cairo to Barbourville.