There are 922.31 miles from Lyons to Twisp in northwest direction and 1,250 miles (2,011.68 kilometers) by car, following the I-25 route.
Lyons and Twisp are 22 hours 7 mins far apart, if you drive non-stop .
This is the fastest route from Lyons, CO to Twisp, WA.
Please note the time difference between Lyons, CO and Twisp, WA is 1 hour. The current time in Lyons is 8:57 pm and the current time in Twisp is 7:57 pm.
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