Distance between cities › USA › Ohio › Lyons, OH › Distance from Lyons to Isom Book Hotels

Distance from Lyons, OH to Isom, KY

Distance

395 mi

Time

8 hours 15 mins

Gas Cost

$36 - $70

There are 317.92 miles from Lyons to Isom in southeast direction and 395 miles (635.69 kilometers) by car, following the US-23 route.

Lyons and Isom are 8 hours 15 mins far apart, if you drive non-stop .

This is the fastest route from Lyons, OH to Isom, KY.

Lyons, OH and Isom, KY are in the same time zone (EDT). Current time in both locations is 12:38 am.

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Lowest Price Rental Cars in Lyons, OH

Planning on renting a car to go from Lyons, OH to Isom, KY? Here there are some offers to rent a car in Lyons, OH

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Lyons »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 15.87 gallons of gas to cover the route between Lyons, OH and Isom, KY.

The estimated cost of gas to go from Lyons to Isom is $50.85.

During the route, an average car will release 310.96 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Lyons, OH and Isom, KY

If you want to meet halfway between Lyons, OH and Isom, KY or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.391103 and -82.970182, or 39º 23' 27.9708" N, 82º 58' 12.6552" W. This location is 197.60 miles away from Lyons, OH and Isom, KY and it would take approximately 4 hours 7 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest city to the halfway point is Ross County, OH, situated 202 miles from Lyons, OH and 196 miles from Isom, KY. It would take 4 hours 27 mins to go from Lyons to Ross County and 3 hours 58 mins to go from Isom to Ross County.