There are 494.94 miles from Madison to Lyons in north direction and 589 miles (947.90 kilometers) by car, following the I-65 route.
Madison and Lyons are 11 hours 9 mins far apart, if you drive non-stop .
This is the fastest route from Madison, AL to Lyons, IL. The halfway point is Speed, IN.
Madison, AL and Lyons, IL are in the same time zone (CDT). Current time in both locations is 4:45 am.
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