There are 1,114.54 miles from Madison to Adrian in southeast direction and 1,371 miles (2,206.41 kilometers) by car, following the I-29 route.
Madison and Adrian are 1 day 1 hour far apart, if you drive non-stop .
This is the fastest route from Madison, SD to Adrian, GA. The halfway point is Caseyville, IL.
Please note the time difference between Madison, SD and Adrian, GA is 1 hour. The current time in Madison is 8:28 pm and the current time in Adrian is 9:28 pm.
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