Distance between cities › USA › South Dakota › Madison, SD › Distance from Madison to Isom Book Hotels

Distance from Madison, SD to Isom, KY

Distance

1,126 mi

Time

20 hours 23 mins

Gas Cost

$105 - $204

There are 880.22 miles from Madison to Isom in southeast direction and 1,126 miles (1,812.12 kilometers) by car, following the I-80 route.

Madison and Isom are 20 hours 23 mins far apart, if you drive non-stop .

This is the fastest route from Madison, SD to Isom, KY.

Please note the time difference between Madison, SD and Isom, KY is 1 hour. The current time in Madison is 6:00 am and the current time in Isom is 7:00 am.

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Lowest Price Rental Cars in Madison, SD

Planning on renting a car to go from Madison, SD to Isom, KY? Here there are some offers to rent a car in Madison, SD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Madison »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 45.21 gallons of gas to cover the route between Madison, SD and Isom, KY.

The estimated cost of gas to go from Madison to Isom is $147.47.

During the route, an average car will release 885.70 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Madison, SD and Isom, KY

If you want to meet halfway between Madison, SD and Isom, KY or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 40.902652 and -90.196211, or 40º 54' 9.5472" N, 90º 11' 46.3596" W. This location is 562.83 miles away from Madison, SD and Isom, KY and it would take approximately 10 hours 11 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Gilson, IL, situated 559 miles from Madison, SD and 576 miles from Isom, KY. It would take 10 hours 5 mins to go from Madison to Gilson and 10 hours 34 mins to go from Isom to Gilson.