Distance between cities › USA › South Dakota › Madison, SD › Distance from Madison to Lancaster Book Hotels

Distance from Madison, SD to Lancaster, SC

Distance

1,397 mi

Time

1 day 2 hours

Gas Cost

$128 - $249

There are 1,080.13 miles from Madison to Lancaster in southeast direction and 1,397 miles (2,248.25 kilometers) by car, following the I-29 route.

Madison and Lancaster are 1 day 2 hours far apart, if you drive non-stop .

This is the fastest route from Madison, SD to Lancaster, SC.

Please note the time difference between Madison, SD and Lancaster, SC is 1 hour. The current time in Madison is 1:00 am and the current time in Lancaster is 2:00 am.

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Lowest Price Rental Cars in Madison, SD

Planning on renting a car to go from Madison, SD to Lancaster, SC? Here there are some offers to rent a car in Madison, SD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Madison »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 56.10 gallons of gas to cover the route between Madison, SD and Lancaster, SC.

The estimated cost of gas to go from Madison to Lancaster is $179.76.

During the route, an average car will release 1,099.20 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Madison, SD and Lancaster, SC

If you want to meet halfway between Madison, SD and Lancaster, SC or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 38.479709 and -89.583623, or 38º 28' 46.9524" N, 89º 35' 1.0428" W. This location is 698.50 miles away from Madison, SD and Lancaster, SC and it would take approximately 13 hours 3 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Damiansville, IL, situated 696 miles from Madison, SD and 704 miles from Lancaster, SC. It would take 12 hours 50 mins to go from Madison to Damiansville and 13 hours 23 mins to go from Lancaster to Damiansville.