Distance between cities › USA › Illinois › McCook, IL › Distance from McCook to Cairo Book Hotels

Distance from McCook, IL to Cairo, WV

Distance

497 mi

Time

9 hours 40 mins

Gas Cost

$46 - $90

There are 393.76 miles from McCook to Cairo in southeast direction and 497 miles (799.84 kilometers) by car, following the I-65 route.

McCook and Cairo are 9 hours 40 mins far apart, if you drive non-stop .

This is the fastest route from McCook, IL to Cairo, WV. The halfway point is Webster, IN.

Please note the time difference between McCook, IL and Cairo, WV is 1 hour. The current time in McCook is 6:28 pm and the current time in Cairo is 7:28 pm.

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Lowest Price Rental Cars in McCook, IL

Planning on renting a car to go from McCook, IL to Cairo, WV? Here there are some offers to rent a car in McCook, IL

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in McCook »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 19.96 gallons of gas to cover the route between McCook, IL and Cairo, WV.

The estimated cost of gas to go from McCook to Cairo is $65.12.

During the route, an average car will release 391.11 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between McCook, IL and Cairo, WV

If you want to meet halfway between McCook, IL and Cairo, WV or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.870853 and -84.933159, or 39º 52' 15.0708" N, 84º 55' 59.3724" W. This location is 248.53 miles away from McCook, IL and Cairo, WV and it would take approximately 4 hours 50 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Webster, IN, situated 257 miles from McCook, IL and 246 miles from Cairo, WV. It would take 4 hours 19 mins to go from McCook to Webster and 4 hours 1 min to go from Cairo to Webster.