Distance between cities › USA › Illinois › McCook, IL › Distance from McCook to Florence Book Hotels

Distance from McCook, IL to Florence, MO

Distance

440 mi

Time

8 hours 36 mins

Gas Cost

$41 - $80

There are 350.31 miles from McCook to Florence in southwest direction and 440 miles (708.11 kilometers) by car, following the I-55 route.

McCook and Florence are 8 hours 36 mins far apart, if you drive non-stop .

This is the fastest route from McCook, IL to Florence, MO. The halfway point is Jacksonville, IL.

McCook, IL and Florence, MO are in the same time zone (CDT). Current time in both locations is 10:07 am.

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Lowest Price Rental Cars in McCook, IL

Planning on renting a car to go from McCook, IL to Florence, MO? Here there are some offers to rent a car in McCook, IL

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in McCook »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 17.68 gallons of gas to cover the route between McCook, IL and Florence, MO.

The estimated cost of gas to go from McCook to Florence is $57.66.

During the route, an average car will release 346.33 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between McCook, IL and Florence, MO

If you want to meet halfway between McCook, IL and Florence, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.705582 and -90.215164, or 39º 42' 20.0952" N, 90º 12' 54.5904" W. This location is 220.08 miles away from McCook, IL and Florence, MO and it would take approximately 4 hours 18 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Jacksonville, IL, situated 224 miles from McCook, IL and 214 miles from Florence, MO. It would take 3 hours 29 mins to go from McCook to Jacksonville and 3 hours 50 mins to go from Florence to Jacksonville.

Major City Closest to Halfway Point

The major city closest to the halfway point between McCook, IL and Florence, MO is Springfield, IL, situated 190 miles from McCook, IL and 246 miles from Florence, MO. It would take 3 hours to go from McCook to and 4 hours 18 mins to go from Florence to Springfield.