There are 320.60 miles from McCook to Fredericktown in southwest direction and 371 miles (597.07 kilometers) by car, following the I-55 route.
McCook and Fredericktown are 7 hours far apart, if you drive non-stop .
This is the fastest route from McCook, IL to Fredericktown, MO. The halfway point is Bissell, IL.
McCook, IL and Fredericktown, MO are in the same time zone (CDT). Current time in both locations is 11:38 am.
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