Distance between cities › USA › Arizona › Mesa, AZ › Distance from Mesa to Adrian Book Hotels

Distance from Mesa, AZ to Adrian, MO

Distance

1,267 mi

Time

22 hours 26 mins

Gas Cost

$118 - $230

There are 1,035.03 miles from Mesa to Adrian in northeast direction and 1,267 miles (2,039.04 kilometers) by car, following the I-40 and AZ 77 route.

Mesa and Adrian are 22 hours 26 mins far apart, if you drive non-stop .

This is the fastest route from Mesa, AZ to Adrian, MO. The halfway point is Adrian, TX.

Please note the time difference between Mesa, AZ and Adrian, MO is 2 hours. The current time in Mesa is 2:13 am and the current time in Adrian is 4:13 am.

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Lowest Price Rental Cars in Mesa, AZ

Planning on renting a car to go from Mesa, AZ to Adrian, MO? Here there are some offers to rent a car in Mesa, AZ

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Mesa »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 50.88 gallons of gas to cover the route between Mesa, AZ and Adrian, MO.

The estimated cost of gas to go from Mesa to Adrian is $165.96.

During the route, an average car will release 996.80 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Mesa, AZ and Adrian, MO

If you want to meet halfway between Mesa, AZ and Adrian, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.269421 and -102.721657, or 35º 16' 9.9156" N, 102º 43' 17.9652" W. This location is 633.43 miles away from Mesa, AZ and Adrian, MO and it would take approximately 11 hours 13 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Adrian, TX, situated 642 miles from Mesa, AZ and 626 miles from Adrian, MO. It would take 9 hours 34 mins to go from Mesa to Adrian and 9 hours 11 mins to go from Adrian to Adrian.