Distance between cities › USA › Arizona › Mesa, AZ › Distance from Mesa to Appleton City Book Hotels

Distance from Mesa, AZ to Appleton City, MO

Distance

1,272 mi

Time

22 hours 34 mins

Gas Cost

$119 - $231

There are 1,048.68 miles from Mesa to Appleton City in northeast direction and 1,272 miles (2,047.09 kilometers) by car, following the I-40 and AZ 77 route.

Mesa and Appleton City are 22 hours 34 mins far apart, if you drive non-stop .

This is the fastest route from Mesa, AZ to Appleton City, MO. The halfway point is Adrian, TX.

Please note the time difference between Mesa, AZ and Appleton City, MO is 2 hours. The current time in Mesa is 2:12 am and the current time in Appleton City is 4:12 am.

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Lowest Price Rental Cars in Mesa, AZ

Planning on renting a car to go from Mesa, AZ to Appleton City, MO? Here there are some offers to rent a car in Mesa, AZ

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Mesa »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 51.09 gallons of gas to cover the route between Mesa, AZ and Appleton City, MO.

The estimated cost of gas to go from Mesa to Appleton City is $166.66.

During the route, an average car will release 1,000.96 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Mesa, AZ and Appleton City, MO

If you want to meet halfway between Mesa, AZ and Appleton City, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.260452 and -102.649483, or 35º 15' 37.6272" N, 102º 38' 58.1388" W. This location is 636.07 miles away from Mesa, AZ and Appleton City, MO and it would take approximately 11 hours 17 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Adrian, TX, situated 642 miles from Mesa, AZ and 632 miles from Appleton City, MO. It would take 9 hours 34 mins to go from Mesa to Adrian and 9 hours 31 mins to go from Appleton City to Adrian.