Distance between cities › USA › Ohio › Mesopotamia, OH › Distance from Mesopotamia to Argyle Book Hotels

Distance from Mesopotamia, OH to Argyle, MO

Distance

719 mi

Time

13 hours 54 mins

Gas Cost

$66 - $128

There are 625.37 miles from Mesopotamia to Argyle in southwest direction and 719 miles (1,157.12 kilometers) by car, following the I-70 route.

Mesopotamia and Argyle are 13 hours 54 mins far apart, if you drive non-stop .

This is the fastest route from Mesopotamia, OH to Argyle, MO.

Please note the time difference between Mesopotamia, OH and Argyle, MO is 1 hour. The current time in Mesopotamia is 4:33 pm and the current time in Argyle is 3:33 pm.

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Lowest Price Rental Cars in Mesopotamia, OH

Planning on renting a car to go from Mesopotamia, OH to Argyle, MO? Here there are some offers to rent a car in Mesopotamia, OH

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Mesopotamia »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 28.86 gallons of gas to cover the route between Mesopotamia, OH and Argyle, MO.

The estimated cost of gas to go from Mesopotamia to Argyle is $92.47.

During the route, an average car will release 565.47 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Mesopotamia, OH and Argyle, MO

If you want to meet halfway between Mesopotamia, OH and Argyle, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.688607 and -86.322387, or 39º 41' 18.9852" N, 86º 19' 20.5932" W. This location is 359.33 miles away from Mesopotamia, OH and Argyle, MO and it would take approximately 6 hours 57 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Bridgeport, IN, situated 358 miles from Mesopotamia, OH and 363 miles from Argyle, MO. It would take 6 hours 59 mins to go from Mesopotamia to Bridgeport and 7 hours 2 mins to go from Argyle to Bridgeport.

Major City Closest to Halfway Point

The major city closest to the halfway point between Mesopotamia, OH and Argyle, MO is Indianapolis, IN, situated 347 miles from Mesopotamia, OH and 372 miles from Argyle, MO. It would take 6 hours 47 mins to go from Mesopotamia to Indianapolis and 7 hours 14 mins to go from Argyle to Indianapolis.