Distance between cities › USA › Ohio › Mesopotamia, OH › Distance from Mesopotamia to Ithaca Book Hotels

Distance from Mesopotamia, OH to Ithaca, MI

Distance

314 mi

Time

6 hours 3 mins

Gas Cost

$29 - $56

There are 224.67 miles from Mesopotamia to Ithaca in northwest direction and 314 miles (505.33 kilometers) by car, following the I-80 route.

Mesopotamia and Ithaca are 6 hours 3 mins far apart, if you drive non-stop .

This is the fastest route from Mesopotamia, OH to Ithaca, MI.

Mesopotamia, OH and Ithaca, MI are in the same time zone (EDT). Current time in both locations is 12:39 am.

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Lowest Price Rental Cars in Mesopotamia, OH

Planning on renting a car to go from Mesopotamia, OH to Ithaca, MI? Here there are some offers to rent a car in Mesopotamia, OH

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Mesopotamia »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 12.60 gallons of gas to cover the route between Mesopotamia, OH and Ithaca, MI.

The estimated cost of gas to go from Mesopotamia to Ithaca is $40.38.

During the route, an average car will release 246.94 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Mesopotamia, OH and Ithaca, MI

If you want to meet halfway between Mesopotamia, OH and Ithaca, MI or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 41.541442 and -83.519292, or 41º 32' 29.1912" N, 83º 31' 9.4512" W. This location is 156.92 miles away from Mesopotamia, OH and Ithaca, MI and it would take approximately 3 hours 1 min to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Stony Ridge, OH, situated 147 miles from Mesopotamia, OH and 171 miles from Ithaca, MI. It would take 3 hours 1 min to go from Mesopotamia to Stony Ridge and 3 hours 9 mins to go from Ithaca to Stony Ridge.

Major City Closest to Halfway Point

The major city closest to the halfway point between Mesopotamia, OH and Ithaca, MI is Toledo, OH, situated 156 miles from Mesopotamia, OH and 158 miles from Ithaca, MI. It would take 3 hours 14 mins to go from Mesopotamia to Toledo and 2 hours 56 mins to go from Ithaca to Toledo.