Distance between cities › USA › Ohio › Mesopotamia, OH › Distance from Mesopotamia to Wheeling Book Hotels

Distance from Mesopotamia, OH to Wheeling, MO

Distance

765 mi

Time

14 hours 32 mins

Gas Cost

$71 - $139

There are 660.97 miles from Mesopotamia to Wheeling in west direction and 765 miles (1,231.15 kilometers) by car, following the I-70 route.

Mesopotamia and Wheeling are 14 hours 32 mins far apart, if you drive non-stop .

This is the fastest route from Mesopotamia, OH to Wheeling, MO.

Please note the time difference between Mesopotamia, OH and Wheeling, MO is 1 hour. The current time in Mesopotamia is 11:16 am and the current time in Wheeling is 10:16 am.

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Lowest Price Rental Cars in Mesopotamia, OH

Planning on renting a car to go from Mesopotamia, OH to Wheeling, MO? Here there are some offers to rent a car in Mesopotamia, OH

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Mesopotamia »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 30.71 gallons of gas to cover the route between Mesopotamia, OH and Wheeling, MO.

The estimated cost of gas to go from Mesopotamia to Wheeling is $100.17.

During the route, an average car will release 601.65 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Mesopotamia, OH and Wheeling, MO

If you want to meet halfway between Mesopotamia, OH and Wheeling, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 40.057055 and -86.82523, or 40º 3' 25.398" N, 86º 49' 30.828" W. This location is 382.33 miles away from Mesopotamia, OH and Wheeling, MO and it would take approximately 7 hours 16 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Crawfordsville, IN, situated 392 miles from Mesopotamia, OH and 376 miles from Wheeling, MO. It would take 7 hours 42 mins to go from Mesopotamia to Crawfordsville and 6 hours 59 mins to go from Wheeling to Crawfordsville.