Distance between cities › USA › Mississippi › Nicholson, MS › Distance from Nicholson to Jeffersonville Book Hotels

Distance from Nicholson, MS to Jeffersonville, IN

Distance

662 mi

Time

12 hours 2 mins

Gas Cost

$62 - $121

There are 584.11 miles from Nicholson to Jeffersonville in northeast direction and 662 miles (1,065.39 kilometers) by car, following the I-65 route.

Nicholson and Jeffersonville are 12 hours 2 mins far apart, if you drive non-stop .

This is the fastest route from Nicholson, MS to Jeffersonville, IN.

Please note the time difference between Nicholson, MS and Jeffersonville, IN is 1 hour. The current time in Nicholson is 1:57 am and the current time in Jeffersonville is 2:57 am.

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Lowest Price Rental Cars in Nicholson, MS

Planning on renting a car to go from Nicholson, MS to Jeffersonville, IN? Here there are some offers to rent a car in Nicholson, MS

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Nicholson »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 26.60 gallons of gas to cover the route between Nicholson, MS and Jeffersonville, IN.

The estimated cost of gas to go from Nicholson to Jeffersonville is $87.55.

During the route, an average car will release 521.21 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.29 per gallon of regular gas. Price last updated on March 13, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Nicholson, MS and Jeffersonville, IN

If you want to meet halfway between Nicholson, MS and Jeffersonville, IN or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 33.926798 and -86.86722, or 33º 55' 36.4728" N, 86º 52' 1.992" W. This location is 331.21 miles away from Nicholson, MS and Jeffersonville, IN and it would take approximately 6 hours 1 min to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Hayden, AL, situated 325 miles from Nicholson, MS and 348 miles from Jeffersonville, IN. It would take 5 hours 56 mins to go from Nicholson to Hayden and 6 hours 25 mins to go from Jeffersonville to Hayden.

Major City Closest to Halfway Point

The major city closest to the halfway point between Nicholson, MS and Jeffersonville, IN is Birmingham, AL, situated 298 miles from Nicholson, MS and 368 miles from Jeffersonville, IN. It would take 5 hours 23 mins to go from Nicholson to Birmingham and 6 hours 46 mins to go from Jeffersonville to Birmingham.