Distance between cities › USA › Mississippi › Nicholson, MS › Distance from Nicholson to Ruffin Book Hotels

Distance from Nicholson, MS to Ruffin, SC

Distance

676 mi

Time

12 hours 51 mins

Gas Cost

$62 - $120

There are 549.90 miles from Nicholson to Ruffin in northeast direction and 676 miles (1,087.92 kilometers) by car, following the I-59 route.

Nicholson and Ruffin are 12 hours 51 mins far apart, if you drive non-stop .

This is the fastest route from Nicholson, MS to Ruffin, SC. The halfway point is Opelika, AL.

Please note the time difference between Nicholson, MS and Ruffin, SC is 1 hour. The current time in Nicholson is 12:16 am and the current time in Ruffin is 1:16 am.

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Lowest Price Rental Cars in Nicholson, MS

Planning on renting a car to go from Nicholson, MS to Ruffin, SC? Here there are some offers to rent a car in Nicholson, MS

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Nicholson »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 27.15 gallons of gas to cover the route between Nicholson, MS and Ruffin, SC.

The estimated cost of gas to go from Nicholson to Ruffin is $87.

During the route, an average car will release 532.02 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Nicholson, MS and Ruffin, SC

If you want to meet halfway between Nicholson, MS and Ruffin, SC or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 32.643181 and -85.350861, or 32º 38' 35.4516" N, 85º 21' 3.0996" W. This location is 338.08 miles away from Nicholson, MS and Ruffin, SC and it would take approximately 6 hours 25 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Opelika, AL, situated 341 miles from Nicholson, MS and 339 miles from Ruffin, SC. It would take 5 hours 6 mins to go from Nicholson to Opelika and 5 hours 31 mins to go from Ruffin to Opelika.

Major City Closest to Halfway Point

The major city closest to the halfway point between Nicholson, MS and Ruffin, SC is Columbus, GA, situated 367 miles from Nicholson, MS and 312 miles from Ruffin, SC. It would take 5 hours 34 mins to go from Nicholson to and 5 hours 7 mins to go from Ruffin to Columbus.