Distance between cities › USA › Mississippi › Nicholson, MS › Distance from Nicholson to Upton Book Hotels

Distance from Nicholson, MS to Upton, KY

Distance

601 mi

Time

10 hours 52 mins

Gas Cost

$55 - $107

There are 529.52 miles from Nicholson to Upton in northeast direction and 601 miles (967.22 kilometers) by car, following the I-65 route.

Nicholson and Upton are 10 hours 52 mins far apart, if you drive non-stop .

This is the fastest route from Nicholson, MS to Upton, KY.

Please note the time difference between Nicholson, MS and Upton, KY is 1 hour. The current time in Nicholson is 7:40 pm and the current time in Upton is 8:40 pm.

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Lowest Price Rental Cars in Nicholson, MS

Planning on renting a car to go from Nicholson, MS to Upton, KY? Here there are some offers to rent a car in Nicholson, MS

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Nicholson »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 24.14 gallons of gas to cover the route between Nicholson, MS and Upton, KY.

The estimated cost of gas to go from Nicholson to Upton is $77.36.

During the route, an average car will release 473.04 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Nicholson, MS and Upton, KY

If you want to meet halfway between Nicholson, MS and Upton, KY or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 33.520881 and -86.846079, or 33º 31' 15.1716" N, 86º 50' 45.8844" W. This location is 300.60 miles away from Nicholson, MS and Upton, KY and it would take approximately 5 hours 26 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest and also the major city is Birmingham, AL, situated 298.17 miles from Nicholson, MS and 306.71 miles from Upton, KY. It would take 5 hours 23 mins to go from Nicholson to Birmingham and 5 hours 35 mins to go from Upton to Birmingham.