Distance between cities › USA › Missouri › Old Appleton, MO › Distance from Old Appleton to Willoughby Book Hotels

Distance from Old Appleton, MO to Willoughby, OH

Distance

645 mi

Time

12 hours 33 mins

Gas Cost

$59 - $115

There are 522.56 miles from Old Appleton to Willoughby in northeast direction and 645 miles (1,038.03 kilometers) by car, following the I-70 route.

Old Appleton and Willoughby are 12 hours 33 mins far apart, if you drive non-stop .

This is the fastest route from Old Appleton, MO to Willoughby, OH.

Please note the time difference between Old Appleton, MO and Willoughby, OH is 1 hour. The current time in Old Appleton is 12:00 am and the current time in Willoughby is 1:00 am.

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Lowest Price Rental Cars in Old Appleton, MO

Planning on renting a car to go from Old Appleton, MO to Willoughby, OH? Here there are some offers to rent a car in Old Appleton, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Old Appleton »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 25.90 gallons of gas to cover the route between Old Appleton, MO and Willoughby, OH.

The estimated cost of gas to go from Old Appleton to Willoughby is $82.98.

During the route, an average car will release 507.43 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Old Appleton, MO and Willoughby, OH

If you want to meet halfway between Old Appleton, MO and Willoughby, OH or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.803475 and -85.96558, or 39º 48' 12.51" N, 85º 57' 56.088" W. This location is 322.46 miles away from Old Appleton, MO and Willoughby, OH and it would take approximately 6 hours 16 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Cumberland, IN, situated 326 miles from Old Appleton, MO and 322 miles from Willoughby, OH. It would take 6 hours 34 mins to go from Old Appleton to Cumberland and 6 hours 8 mins to go from Willoughby to Cumberland.

Major City Closest to Halfway Point

The major city closest to the halfway point between Old Appleton, MO and Willoughby, OH is Indianapolis, IN, situated 313 miles from Old Appleton, MO and 332 miles from Willoughby, OH. It would take 6 hours 18 mins to go from Old Appleton to Indianapolis and 6 hours 21 mins to go from Willoughby to Indianapolis.