Distance between cities › USA › Maryland › Poolesville, MD › Distance from Poolesville to Cairo Book Hotels

Distance from Poolesville, MD to Cairo, WV

Distance

272 mi

Time

5 hours 15 mins

Gas Cost

$25 - $49

There are 200.37 miles from Poolesville to Cairo in west direction and 272 miles (437.74 kilometers) by car, following the US-40 route.

Poolesville and Cairo are 5 hours 15 mins far apart, if you drive non-stop .

This is the fastest route from Poolesville, MD to Cairo, WV.

Poolesville, MD and Cairo, WV are in the same time zone (EDT). Current time in both locations is 5:09 am.

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Lowest Price Rental Cars in Poolesville, MD

Planning on renting a car to go from Poolesville, MD to Cairo, WV? Here there are some offers to rent a car in Poolesville, MD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Poolesville »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 10.92 gallons of gas to cover the route between Poolesville, MD and Cairo, WV.

The estimated cost of gas to go from Poolesville to Cairo is $35.63.

During the route, an average car will release 213.99 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Poolesville, MD and Cairo, WV

If you want to meet halfway between Poolesville, MD and Cairo, WV or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.689495 and -79.189174, or 39º 41' 22.182" N, 79º 11' 21.0264" W. This location is 135.98 miles away from Poolesville, MD and Cairo, WV and it would take approximately 2 hours 37 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Grantsville, MD, situated 136 miles from Poolesville, MD and 137 miles from Cairo, WV. It would take 2 hours 39 mins to go from Poolesville to Grantsville and 2 hours 38 mins to go from Cairo to Grantsville.