Distance between cities › USA › Minnesota › Saint Cloud, MN › Distance from Saint Cloud to Defiance Book Hotels

Distance from Saint Cloud, MN to Defiance, MO

Distance

600 mi

Time

11 hours 36 mins

Gas Cost

$55 - $107

There are 508.87 miles from Saint Cloud to Defiance in southeast direction and 600 miles (965.61 kilometers) by car, following the I-35W route.

Saint Cloud and Defiance are 11 hours 36 mins far apart, if you drive non-stop .

This is the fastest route from Saint Cloud, MN to Defiance, MO. The halfway point is Gilbertville, IA.

Saint Cloud, MN and Defiance, MO are in the same time zone (CDT). Current time in both locations is 11:59 pm.

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Lowest Price Rental Cars in Saint Cloud, MN

Planning on renting a car to go from Saint Cloud, MN to Defiance, MO? Here there are some offers to rent a car in Saint Cloud, MN

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Saint Cloud »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 24.08 gallons of gas to cover the route between Saint Cloud, MN and Defiance, MO.

The estimated cost of gas to go from Saint Cloud to Defiance is $77.14.

During the route, an average car will release 471.72 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Saint Cloud, MN and Defiance, MO

If you want to meet halfway between Saint Cloud, MN and Defiance, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 42.414246 and -92.224335, or 42º 24' 51.2856" N, 92º 13' 27.606" W. This location is 299.76 miles away from Saint Cloud, MN and Defiance, MO and it would take approximately 5 hours 48 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Gilbertville, IA, situated 297 miles from Saint Cloud, MN and 308 miles from Defiance, MO. It would take 4 hours 36 mins to go from Saint Cloud to Gilbertville and 5 hours 9 mins to go from Defiance to Gilbertville.