Distance between cities › USA › Missouri › Saint James, MO › Distance from Saint James to Hampton Book Hotels

Distance from Saint James, MO to Hampton, SC

Distance

846 mi

Time

16 hours 20 mins

Gas Cost

$79 - $153

There are 687.53 miles from Saint James to Hampton in southeast direction and 846 miles (1,361.51 kilometers) by car, following the I-24 route.

Saint James and Hampton are 16 hours 20 mins far apart, if you drive non-stop .

This is the fastest route from Saint James, MO to Hampton, SC.

Please note the time difference between Saint James, MO and Hampton, SC is 1 hour. The current time in Saint James is 3:27 pm and the current time in Hampton is 4:27 pm.

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Lowest Price Rental Cars in Saint James, MO

Planning on renting a car to go from Saint James, MO to Hampton, SC? Here there are some offers to rent a car in Saint James, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Saint James »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 33.96 gallons of gas to cover the route between Saint James, MO and Hampton, SC.

The estimated cost of gas to go from Saint James to Hampton is $110.79.

During the route, an average car will release 665.41 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Saint James, MO and Hampton, SC

If you want to meet halfway between Saint James, MO and Hampton, SC or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.790803 and -86.376091, or 35º 47' 26.8908" N, 86º 22' 33.9276" W. This location is 422.84 miles away from Saint James, MO and Hampton, SC and it would take approximately 8 hours 10 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest and also the major city is Murfreesboro, TN, situated 415.9 miles from Saint James, MO and 432.09 miles from Hampton, SC. It would take 7 hours 59 mins to go from Saint James to Murfreesboro and 8 hours 29 mins to go from Hampton to Murfreesboro.