Distance between cities › USA › Missouri › Saint James, MO › Distance from Saint James to Highmore Book Hotels

Distance from Saint James, MO to Highmore, SD

Distance

776 mi

Time

14 hours 12 mins

Gas Cost

$72 - $141

There are 606.44 miles from Saint James to Highmore in northwest direction and 776 miles (1,248.85 kilometers) by car, following the I-29 and US-6 route.

Saint James and Highmore are 14 hours 12 mins far apart, if you drive non-stop .

This is the fastest route from Saint James, MO to Highmore, SD.

Saint James, MO and Highmore, SD are in the same time zone (CDT). Current time in both locations is 7:06 pm.

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Lowest Price Rental Cars in Saint James, MO

Planning on renting a car to go from Saint James, MO to Highmore, SD? Here there are some offers to rent a car in Saint James, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Saint James »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 31.17 gallons of gas to cover the route between Saint James, MO and Highmore, SD.

The estimated cost of gas to go from Saint James to Highmore is $101.66.

During the route, an average car will release 610.60 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Saint James, MO and Highmore, SD

If you want to meet halfway between Saint James, MO and Highmore, SD or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 41.08673 and -95.829481, or 41º 5' 12.228" N, 95º 49' 46.1316" W. This location is 388.01 miles away from Saint James, MO and Highmore, SD and it would take approximately 7 hours 6 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Pacific Junction, IA, situated 385 miles from Saint James, MO and 391 miles from Highmore, SD. It would take 7 hours 17 mins to go from Saint James to Pacific Junction and 6 hours 59 mins to go from Highmore to Pacific Junction.

Major City Closest to Halfway Point

The major city closest to the halfway point between Saint James, MO and Highmore, SD is Omaha, NE, situated 411 miles from Saint James, MO and 376 miles from Highmore, SD. It would take 7 hours 46 mins to go from Saint James to Omaha and 6 hours 45 mins to go from Highmore to Omaha.