Distance between cities › USA › Missouri › Saint James, MO › Distance from Saint James to Mathiston Book Hotels

Distance from Saint James, MO to Mathiston, MS

Distance

443 mi

Time

8 hours 48 mins

Gas Cost

$41 - $80

There are 338.09 miles from Saint James to Mathiston in southeast direction and 443 miles (712.94 kilometers) by car, following the I-55 route.

Saint James and Mathiston are 8 hours 48 mins far apart, if you drive non-stop .

This is the fastest route from Saint James, MO to Mathiston, MS.

Saint James, MO and Mathiston, MS are in the same time zone (CDT). Current time in both locations is 5:55 pm.

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Lowest Price Rental Cars in Saint James, MO

Planning on renting a car to go from Saint James, MO to Mathiston, MS? Here there are some offers to rent a car in Saint James, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Saint James »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 17.79 gallons of gas to cover the route between Saint James, MO and Mathiston, MS.

The estimated cost of gas to go from Saint James to Mathiston is $58.02.

During the route, an average car will release 348.46 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Saint James, MO and Mathiston, MS

If you want to meet halfway between Saint James, MO and Mathiston, MS or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.807054 and -90.681697, or 35º 48' 25.3944" N, 90º 40' 54.1092" W. This location is 221.44 miles away from Saint James, MO and Mathiston, MS and it would take approximately 4 hours 24 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is State University, AR, situated 218 miles from Saint James, MO and 227 miles from Mathiston, MS. It would take 4 hours 45 mins to go from Saint James to State University and 4 hours 13 mins to go from Mathiston to State University.