Distance between cities › USA › Missouri › Saint James, MO › Distance from Saint James to Monroe Book Hotels

Distance from Saint James, MO to Monroe, SD

Distance

598 mi

Time

11 hours 18 mins

Gas Cost

$56 - $108

There are 479.13 miles from Saint James to Monroe in northwest direction and 598 miles (962.39 kilometers) by car, following the I-29 and US-6 route.

Saint James and Monroe are 11 hours 18 mins far apart, if you drive non-stop .

This is the fastest route from Saint James, MO to Monroe, SD.

Saint James, MO and Monroe, SD are in the same time zone (CDT). Current time in both locations is 4:39 pm.

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Lowest Price Rental Cars in Saint James, MO

Planning on renting a car to go from Saint James, MO to Monroe, SD? Here there are some offers to rent a car in Saint James, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Saint James »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 24 gallons of gas to cover the route between Saint James, MO and Monroe, SD.

The estimated cost of gas to go from Saint James to Monroe is $78.28.

During the route, an average car will release 470.17 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Saint James, MO and Monroe, SD

If you want to meet halfway between Saint James, MO and Monroe, SD or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.938588 and -94.933983, or 39º 56' 18.9168" N, 94º 56' 2.3388" W. This location is 298.77 miles away from Saint James, MO and Monroe, SD and it would take approximately 5 hours 39 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Amazonia, MO, situated 286 miles from Saint James, MO and 312 miles from Monroe, SD. It would take 5 hours 33 mins to go from Saint James to Amazonia and 5 hours 52 mins to go from Monroe to Amazonia.