Distance between cities › USA › Missouri › Saint James, MO › Distance from Saint James to Seneca Book Hotels

Distance from Saint James, MO to Seneca, MO

Distance

205 mi

Time

3 hours 48 mins

Gas Cost

$18 - $35

There are 182.80 miles from Saint James to Seneca in southwest direction and 205 miles (329.92 kilometers) by car, following the I-44 route.

Saint James and Seneca are 3 hours 48 mins far apart, if you drive non-stop .

This is the fastest route from Saint James, MO to Seneca, MO. The halfway point is Strafford, MO.

Saint James, MO and Seneca, MO are in the same time zone (CDT). Current time in both locations is 2:03 pm.

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Lowest Price Rental Cars in Saint James, MO

Planning on renting a car to go from Saint James, MO to Seneca, MO? Here there are some offers to rent a car in Saint James, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Saint James »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 8.22 gallons of gas to cover the route between Saint James, MO and Seneca, MO.

The estimated cost of gas to go from Saint James to Seneca is $25.39.

During the route, an average car will release 161.05 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.09 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Saint James, MO and Seneca, MO

If you want to meet halfway between Saint James, MO and Seneca, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 37.272182 and -93.062737, or 37º 16' 19.8552" N, 93º 3' 45.8532" W. This location is 102.34 miles away from Saint James, MO and Seneca, MO and it would take approximately 1 hour 54 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Strafford, MO, situated 108 miles from Saint James, MO and 98 miles from Seneca, MO. It would take 1 hour 35 mins to go from Saint James to Strafford and 1 hour 33 mins to go from Seneca to Strafford.

Major City Closest to Halfway Point

The major city closest to the halfway point between Saint James, MO and Seneca, MO is Springfield, MO, situated 121 miles from Saint James, MO and 87 miles from Seneca, MO. It would take 1 hour 50 mins to go from Saint James to and 1 hour 27 mins to go from Seneca to Springfield.