Distance between cities › USA › Texas › Santa Fe, TX › Distance from Santa Fe to Appleton Book Hotels

Distance from Santa Fe, TX to Appleton, ME

Distance

2,033 mi

Time

1 day 14 hours

Gas Cost

$186 - $362

There are 1,749.87 miles from Santa Fe to Appleton in northeast direction and 2,033 miles (3,271.80 kilometers) by car, following the I-81 route.

Santa Fe and Appleton are 1 day 14 hours far apart, if you drive non-stop .

This is the fastest route from Santa Fe, TX to Appleton, ME. The halfway point is Blountville, TN.

Please note the time difference between Santa Fe, TX and Appleton, ME is 1 hour. The current time in Santa Fe is 7:36 pm and the current time in Appleton is 8:36 pm.

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Lowest Price Rental Cars in Santa Fe, TX

Planning on renting a car to go from Santa Fe, TX to Appleton, ME? Here there are some offers to rent a car in Santa Fe, TX

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Santa Fe »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 81.65 gallons of gas to cover the route between Santa Fe, TX and Appleton, ME.

The estimated cost of gas to go from Santa Fe to Appleton is $261.60.

During the route, an average car will release 1,599.62 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Santa Fe, TX and Appleton, ME

If you want to meet halfway between Santa Fe, TX and Appleton, ME or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 36.513809 and -82.397339, or 36º 30' 49.7124" N, 82º 23' 50.4204" W. This location is 1,016.50 miles away from Santa Fe, TX and Appleton, ME and it would take approximately 19 hours 22 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Blountville, TN, situated 1,038 miles from Santa Fe, TX and 998 miles from Appleton, ME. It would take 15 hours 57 mins to go from Santa Fe to Blountville and 16 hours 15 mins to go from Appleton to Blountville.